Reaktion #4336

Reaktionsgleichung

2,5-dibromo-4-nitroaniline

compound B

2,5-dibromo-4-nitroaniline

ethanolamine

→

2-β-hydroxyethylamino-4-amino-5-bromonitrobenzene

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONhave been added
2. 2
   TemperaturThe mixture is heated
3. 3
   TemperaturAfter cooling
4. 4
   Sonstigedilution of the reaction mixture with 100 ml of iced water, the expected product precipitates

Vorschrift

0.02 mole (5.92 g) of 2,5-dibromo-4-nitroaniline (compound B) is added to 15 ml of 96° ethanol to which 12 ml of ethanolamine have been added. The mixture is heated in refluxing alcohol for 6 h 30 min. After cooling and dilution of the reaction mixture with 100 ml of iced water, the expected product precipitates.

Quelle