Reaktion #433393

Reaktionsgleichung

terephthalaldehyde mono(diethyl acetal)

sodium borohydride

→

title product

Ausbeute 90.0%

4-(Diethoxymethyl)benzyl Alcohol

Ausbeute 90.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwhile cooling
2. 2
   SonstigeAfter 5 minutes at room temperature the reaction was quenched with water (50 ml)
3. 3
   Extraktionthe mixture was extracted with ethyl acetate (2×50 ml)
4. 4
   WaschenThe combined extracts were washed with water and brine
5. 5
   Trocknendried over sodium sulfate
6. 6
   Einengenconcentrated in vacuo

Vorschrift

To a solution of terephthalaldehyde mono(diethyl acetal) (1.9 ml, 9.6 mmol) in methanol (35 ml) was added sodium borohydride (1.1 g, 28.8 mmol) while cooling. After 5 minutes at room temperature the reaction was quenched with water (50 ml) and the mixture was extracted with ethyl acetate (2×50 ml). The combined extracts were washed with water and brine, dried over sodium sulfate and concentrated in vacuo, leaving title product as a colorless oil (1.81 g, 90%).

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