Reaktion #433171

ord-47e8bebedc6d4f928ef3e9a96362b9b9

Reaktionsgleichung

CCCCCCOC1CC(C)(C)N(c2nc(Cl)nc(Cl)n2)C(C)(C)C1
product
CCCCCCOC1CC(C)(C)N(c2nc(Cl)nc(Cl)n2)C(C)(C)C1
2,4-Dichloro-6-(2,2,6,6-tetramethyl-4-hexyloxypiperidin-1-yl)-1,3,5-triazine
C1COCCN1
morpholine
→
CCCCCCOC1CC(C)(C)N(c2nc(N3CCOCC3)nc(N3CCOCC3)n2)C(C)(C)C1
2,4-Dimorpholino-6-(2,2,6,6-tetramethyl-4-hexyloxypiperidin-1-yl)-1,3,5-triazine

Edukte

CCCCCCOC1CC(C)(C)N(c2nc(Cl)nc(Cl)n2)C(C)(C)C1
product
CCCCCCOC1CC(C)(C)N(c2nc(Cl)nc(Cl)n2)C(C)(C)C1
2,4-Dichloro-6-(2,2,6,6-tetramethyl-4-hexyloxypiperidin-1-yl)-1,3,5-triazine
C1COCCN1
morpholine

Reagenzien

Keine

Lösungsmittel

O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe crude product precipitating during
  2. 2
    workup.DISSOLUTIONthis is dissolved in ethyl acetate
  3. 3
    Sonstigepurified chromatographically on an SiO2 column

Vorschrift

9.7 g of the product from Example 10 are heated under reflux for 3 hours with 50 ml of morpholine. The orange reaction mixture is poured into water. The crude product precipitating during this is dissolved in ethyl acetate and purified chromatographically on an SiO2 column. The purified product is a viscous material.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05059689uspto-grants-1991_10