Reaktion #4328

Reaktionsgleichung

acetic acid

sodium nitrite

2,5-dibromo-N-benzenesulphonylaniline

nitric acid

→

2,5-dibromo-4-nitro-N-benzenesulphonylaniline

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONare added
2. 2
   TemperaturThe reaction mixture, cooled beforehand
3. 3
   Sonstigethe expected product precipitates
4. 4
   FiltrationIt is filtered off
5. 5
   Waschenwashed to neutrality
6. 6
   Sonstigerecrystallized from acetic acid

Vorschrift

To 250 ml of acetic acid, diluted with 130 ml of water, are added: 1.5 g of sodium nitrite, 0.13 mole of 2,5-dibromo-N-benzenesulphonylaniline prepared in the previous stage and 0.78 mole (32.5 ml) of nitric acid (d=1.52). The reaction mixture is heated for 1 hour at 90° C. The reaction mixture, cooled beforehand, is poured onto 1 kg of ice and the expected product precipitates. It is filtered off, washed to neutrality and then recrystallized from acetic acid; it melts at 148° C.

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