Reaktion #432381

ord-f59042f79eae4811a8b040d8b0813e3c

Reaktionsgleichung

Cc1nc(-c2ccc(-c3ccccc3)cc2)cs1
4-(Biphenyl-4-yl)-2-methyl-thiazole
CCOS(=O)(=O)c1ccc(C)cc1
ethyl p-toluenesulfonate
→
CC[n+]1c(-c2ccc(-c3ccccc3)cc2)csc1C.Cc1ccc(S(=O)(=O)O)cc1
4-(biphenyl-4-yl)-3-ethyl-2-methylthiazolium p-toluenesulfonate

Edukte

Cc1nc(-c2ccc(-c3ccccc3)cc2)cs1
4-(Biphenyl-4-yl)-2-methyl-thiazole
CCOS(=O)(=O)c1ccc(C)cc1
ethyl p-toluenesulfonate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.ADDITIONThe hot mixture is poured onto acetone
  2. 2
    Sonstigeas described in Preparation Example 5(a)

Vorschrift

4-(Biphenyl-4-yl)-2-methyl-thiazole (9.8 pbw) and ethyl p-toluenesulfonate (8.6 pbw) are stirred for 3 hours at 180° C. The hot mixture is poured onto acetone and further processed as described in Preparation Example 5(a).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05055579uspto-grants-1991_10