Reaktion #431814

Reaktionsgleichung

3-allyl-4-hydroxy-5-methoxybenzaldehyde

dimethylformamide

potassium carbonate

1-bromobutane

→

3-allyl-4-butoxy-5-methoxybenzaldehyde

Ausbeute 98.8%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe oil formed
2. 2
   Extraktionwas extracted with dichloromethane
3. 3
   WaschenAfter washing with water
4. 4
   Sonstigedrying
5. 5
   Sonstigeevaporating off the solvent
6. 6
   Sonstigea brown oil was obtained

Vorschrift

A mixture 3-allyl-4-hydroxy-5-methoxybenzaldehyde (10.25 g, 0.053 mole), of dimethylformamide (150 ml), of potassium carbonate (8.29 g, 0.06 mole) and of 1-bromobutane (8.22 g, 0.06 mole) was maintained at 40°-45° C. for 3 hours. The reaction mixture was dropped into iced water and the oil formed was extracted with dichloromethane. After washing with water, drying and evaporating off the solvent, a brown oil was obtained, which was passed through a bed of silica 60 to give a pale yellow oil of 3-allyl-4-butoxy-5-methoxybenzaldehyde (13 g, yield=91%).

Quelle