Reaktion #431383

ord-a2e55b52ec5f46e8b8b746aca8a83878

Reaktionsgleichung

CCCCCN(C(=O)OCC)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C(=O)OC(C)(C)C)cc3)c2c1
tert.butyl 4'-[(2-n-butyl-6-(N-ethoxycarbonyl-n-pentyl-amino)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
ClCCl.O=C(O)C(F)(F)F
trifluoroacetic acid methylene chloride
→
CCCCCN(C(=O)OCC)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2c1
4'-[(2-n-Butyl-6-(N-ethoxycarbonyl-n-pentylamino)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid

Edukte

CCCCCN(C(=O)OCC)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C(=O)OC(C)(C)C)cc3)c2c1
tert.butyl 4'-[(2-n-butyl-6-(N-ethoxycarbonyl-n-pentyl-amino)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
ClCCl.O=C(O)C(F)(F)F
trifluoroacetic acid methylene chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-6-(N-ethoxycarbonyl-n-pentyl-amino)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid/methylene chloride.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05864043uspto-grants-1999_01