Reaktion #43053

ord-1215636967b7414eb8c1f3c627a000b5

Reaktionsgleichung

O=Cc1cccc(-c2ccnc(Cl)n2)c1
Intermediate 1
O=Cc1cccc(-c2ccnc(Cl)n2)c1
3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde
CCN
ethylamine
→
CCNCc1cccc(-c2ccnc(Cl)n2)c1
[3-(2-chloro-pyrimidin-4-yl)-benzyl]-ethyl-amine

Edukte

O=Cc1cccc(-c2ccnc(Cl)n2)c1
Intermediate 1
O=Cc1cccc(-c2ccnc(Cl)n2)c1
3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde
CCN
ethylamine
—
248

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Intermediate 1 was coupled with ethylamine following procedure B. LC-MS showed the product had the expected M+H+ of 248.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07732444B2uspto-grants-2010_06