Reaktion #430450

Reaktionsgleichung

2-nitrobenzyl alcohol

octyl isocyanate

→

o-nitrobenzyl n-octylcarbamate

Ausbeute 62.1%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturheated
2. 2
   Temperaturat reflux under nitrogen for 2 hours
3. 3
   Temperaturcooled
4. 4
   WaschenThe reaction solution was washed with water several times
5. 5
   Trocknenthe resulting toluene solution was then dried over sodium sulfate
6. 6
   FiltrationThe sodium sulfate was filtered off
7. 7
   Sonstigethe solvent was removed from the filtrate on a rotary evaporator
8. 8
   SonstigeThe resulting solid was recrystallized twice from hexane

Vorschrift

100 mL toluene, 10 g 2-nitrobenzyl alcohol, and 11.4 g octyl isocyanate were placed in a 200-mL roundbottom flask, heated at reflux under nitrogen for 2 hours, and then cooled. The reaction solution was washed with water several times and the resulting toluene solution was then dried over sodium sulfate. The sodium sulfate was filtered off and the solvent was removed from the filtrate on a rotary evaporator. The resulting solid was recrystallized twice from hexane, yielding 12.5 g o-nitrobenzyl n-octylcarbamate as light yellow needle-like crystals.

Quelle