Reaktion #42693

Reaktionsgleichung

hydrochloric acid

potassium carbonate

2,3-dichloroquinoxaline

2-chlorobenzenesulfonamide

→

title compound

Ausbeute 101.0%

2-chloro-N-(3-chloroquinoxalin-2-yl)benzenesulfonamide

Ausbeute 101.0%

Lösungsmittel

water

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionextracted with ethyl acetate
2. 2
   WaschenThe residue was washed with a saturated aqueous solution of sodium chloride
3. 3
   Trocknendried with anhydrous magnesium sulfate
4. 4
   Einengenconcentrated

Vorschrift

In the presence of potassium carbonate (625 mg), 2,3-dichloroquinoxaline (275 mg) and 2-chlorobenzenesulfonamide (264 mg) were allowed to react in the solution of dimethylformamide (4 mL) for 3 hours at 90° C. To the reaction mixture, water and hydrochloric acid were added and extracted with ethyl acetate. The residue was washed with a saturated aqueous solution of sodium chloride, dried with anhydrous magnesium sulfate and concentrated to obtain the title compound (493 mg) having the following physical data.

Quelle