Reaktion #426745

Reaktionsgleichung

N-[4-(6-methylimidazo[1,2-a]pyridin-2-yl)phenyl]-4-nitrobenzamide

DCM MeOH

tin (II) chloride dihydrate

→

title compound

Ausbeute 78.2%

4-Amino-N-[4-(6-methylimidazo[1,2-a]pyridin-2-yl)phenyl]benzamide

Ausbeute 78.2%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePrepared

Vorschrift

Prepared as described in the Nitro Reduction section using N-[4-(6-methylimidazo[1,2-a]pyridin-2-yl)phenyl]-4-nitrobenzamide (0.10 g, 0.269 mmol) and tin (II) chloride dihydrate (0.30 g, 1.34 mmol) in EtOH (15 ml) to give the title compound (0.072 g, 78%) as a pale yellow solid after work-up and flash chromatography (15:1 DCM/MeOH).

Quelle