Reaktion #426739

Reaktionsgleichung

6-iodo-2-(4-nitrophenyl)imidazo[1,2-a]pyridine

tin (II) dichloride dihydrate

→

title compound

Ausbeute 73.0%

4-(6-Iodoimidazo[1,2-a]pyridin-2-yl)aniline

Ausbeute 73.0%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePrepared

Vorschrift

Prepared as described in the Nitro Reduction section using 6-iodo-2-(4-nitrophenyl)imidazo[1,2-a]pyridine (0.45 g, 1.23 mmol) and tin (II) dichloride dihydrate (1.39 g, 6.16 mmol) in EtOH (25 ml) to give the title compound (0.301 g, 73%) as a yellow solid, after work-up and flash chromatography (4:1 EtOAc/DCM).

Quelle