Reaktion #426678

Reaktionsgleichung

2-(2-methoxy-4-nitrophenyl)benzothiazole

Hexane THF

tin (II) dichloride dihydrate

→

title compound

Ausbeute 96.0%

2-(4-Amino-2-methoxyphenyl)benzothiazole

Ausbeute 96.0%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePrepared

Vorschrift

Prepared as described in the Nitro Reduction section using 2-(2-methoxy-4-nitrophenyl)benzothiazole (0.1 g, 0.35 mmol) and tin (II) dichloride dihydrate (0.63 g, 2.8 mmol) in EtOH (12 ml) to give the title compound (0.086 g, 96%) as a pale orange solid after work-up and flash chromatography (2:1 Hexane/THF).

Quelle