Reaktion #42625

Reaktionsgleichung

maleic anhydride

sec-butyl amine

→

desired compound

3-(sec-butylcarbamoyl)acrylic acid

Lösungsmittel

diethyl ether

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeformed
2. 2
   Filtrationwhich was recovered by filtration
3. 3
   WaschenThe residue was washed with 2×100 mL diethyl ether
4. 4
   Sonstigedried

Vorschrift

To a stirred solution of maleic anhydride, 95% (42.1 g, 0.4 mol) in 500 mL diethyl ether at 0° C. was added drop wise sec-butyl amine (29.25 g, 0.4 mol) in 50 mL diethyl ether. The resulting mixture was stirred while a solid formed, which was recovered by filtration. The residue was washed with 2×100 mL diethyl ether and dried to yield 51.76 g of the desired compound.

Quelle