Reaktion #425418

Reaktionsgleichung

tert-butyl 3-(4-bromophenoxy)azetidine-1-carboxylate

TFA

→

3-(4-bromophenoxy)azetidine

Ausbeute 100.8%

Lösungsmittel

CH2Cl2

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe reaction mixture was concentrated in vacuo

Vorschrift

To a solution of tert-butyl 3-(4-bromophenoxy)azetidine-1-carboxylate (300 mg, 0.90 mmol) in CH2Cl2 (5 mL) was added TFA (5 mL). The mixture was stirred at room temperature overnight. The reaction mixture was concentrated in vacuo to give 3-(4-bromophenoxy)azetidine (207 mg, 100%) as a yellow oil.

Quelle