Reaktion #421286

Reaktionsgleichung

sodium nitrite

1H-indazol-4-ylamine

sodium tetrafluoroborate

→

1H-indazole-4-diazonium tetrafluoroborate salt

Lösungsmittel

water

hydrochloric acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeA viscous solution resulted
2. 2
   Filtrationwhich was filtered
3. 3
   Waschenwashed briefly with water

Vorschrift

An aqueous solution of sodium nitrite (337 mg, 4.89 mmol) in water (2 mL) was added dropwise to a suspension of 1H-indazol-4-ylamine D (631 mg, 4.74 mmol) in 6M hydrochloric acid (7.2 mL) at below 0° C. After stirring for 30 minutes, sodium tetrafluoroborate (724 mg) was added to the reaction mixture. A viscous solution resulted, which was filtered and washed briefly with water to yield 1H-indazole-4-diazonium tetrafluoroborate salt E (218 mg, 20%) as a deep red solid.

Quelle