Reaktion #42031

Reaktionsgleichung

ethyl 4-(4-methylpiperazin-1-ylmethyl)-3-trifluoromethylbenzoate

hydrochloric acid

→

4-(4-methylpiperazin-1-ylmethyl)-3-trifluoromethylbenzoic acid dihydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeobtained in the step 3

Vorschrift

This compound was prepared in the same manner as in Reference Example 1 (step 6), except that ethyl 4-(4-methylpiperazin-1-ylmethyl)-3-trifluoromethylbenzoate obtained in the step 3 was used, and that the reaction solution was acidified (pH 3) with concentrated hydrochloric acid in place of 1N hydrochloric acid.

Quelle