Reaktion #41993

ord-0630b0abd04f4f82a35413fda4e1b080

Reaktionsgleichung

CCC1(c2c[nH]c3c(N)cccc23)CCc2cc(F)ccc21
3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine
CN(C)S(=O)(=O)Cl
dimethyl sulfamoyl chloride
→
CCC1(c2c[nH]c3c(S(=O)(=O)N(C)C)cccc23)CCc2cc(F)ccc21
title compound
CCC1(c2c[nH]c3c(S(=O)(=O)N(C)C)cccc23)CCc2cc(F)ccc21
7-Dimethylsulfamoyl-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole

Edukte

CCC1(c2c[nH]c3c(N)cccc23)CCc2cc(F)ccc21
3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine
CN(C)S(=O)(=O)Cl
dimethyl sulfamoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Utilizing 3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine and dimethyl sulfamoyl chloride, the title compound is prepared as in example 15. 0.16 g (29%). LC-MS m/z 402.1 (M++1).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07728150B2uspto-grants-2010_06