Reaktion #41957

Reaktionsgleichung

Chloroacetaldehyde diethyl acetal

benzoic acid

potassium iodide

potassium carbonate

→

compound

Ausbeute 56.0%

2-benzoyloxyacetaldehyde Diethyl Acetal

Ausbeute 56.0%

Lösungsmittel

DMF

ethyl acetate

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturby refluxing
2. 2
   FiltrationAfter filtration
3. 3
   Sonstigethe organic layer was separated
4. 4
   Einengenwas subjected to vacuum concentration

Vorschrift

Chloroacetaldehyde diethyl acetal (2.00 g), benzoic acid (2.16 g), potassium iodide (0.27 g), potassium carbonate (1.11 g) and DMF (20 mL) were placed in a three-neck flask, followed by refluxing. Twenty hours later, the reaction mixture was cooled to room temperature, and water (30 mL) and ethyl acetate (80 mL) were added thereto, followed by stirring. After filtration, the organic layer was separated, was subjected to vacuum concentration and thereby yielded the target compound (1.74 g) in a yield of 56%.

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