Reaktion #41955

Reaktionsgleichung

Chloroacetaldehyde diethyl acetal

potassium benzoate

potassium iodide

DMF

→

compound

Ausbeute 84.8%

2-benzoyloxyacetaldehyde Diethyl Acetal

Ausbeute 84.8%

Lösungsmittel

ethyl acetate

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturby refluxing
2. 2
   FiltrationAfter filtration
3. 3
   Sonstigethe organic layer was separated
4. 4
   Einengenwas subjected to vacuum concentration
5. 5
   workup.DISTILLATIONto Kugelrohr distillation at 110-120° C.

Vorschrift

Chloroacetaldehyde diethyl acetal (2.00 g), potassium benzoate (1.91 g), potassium iodide (0.41 g) and DMF (20 mL) were placed in a three-neck flask, followed by refluxing. Twenty hours later, the reaction mixture was cooled to room temperature, and water (30 mL) and ethyl acetate (80 mL) were added thereto, followed by stirring. After filtration, the organic layer was separated, was subjected to vacuum concentration and then to Kugelrohr distillation at 110-120° C. and at 1 mmHg and thereby yielded the target compound (2.41 g) in a yield of 77%.

Quelle