Reaktion #417926

Reaktionsgleichung

sodium hydroxide

33

methyl 4-(undec-4Z-enyloxy)benzoate

→

white solid

Ausbeute 98.1%

4-(undec-4Z-enyloxy)benzoic acid

Ausbeute 98.1%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe solution is refluxed for 20 hours
2. 2
   SonstigeAfter evaporating off the solvent
3. 3
   Extraktionextracted with DCM

Vorschrift

550 μL of 1 N sodium hydroxide solution (550 μmol) are added portionwise to 109 mg of 33 (358 μmol) in methanol (4 mL). The solution is refluxed for 20 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 102 mg of a white solid are obtained, i.e. a yield of 98%.

Quelle