Reaktion #417924

Reaktionsgleichung

sodium hydroxide

29

methyl 2-(undec-4Z-enyloxy)benzoate

→

yellow oil

Ausbeute 99.5%

2-(undec-4Z-enyloxy)benzoic acid

Ausbeute 99.5%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe solution is refluxed for 24 hours
2. 2
   SonstigeAfter evaporating off the solvent
3. 3
   Extraktionextracted with DCM

Vorschrift

500 μL of 1 N sodium hydroxide solution (500 μmol) are added portionwise to 80 mg of 29 (263 μmol) in methanol (3 mL). The solution is refluxed for 24 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 76 mg of a yellow oil are obtained, i.e. a yield of 99%.

Quelle