Reaktion #41784

Reaktionsgleichung

2-Chloro-5-nitropyridine

dimethylamine

H2O

→

2-(dimethylamino)-5-nitropyridine

Lösungsmittel

NMP

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe filtrate that formed
2. 2
   Filtrationwas filtered
3. 3
   Sonstigedried

Vorschrift

2-Chloro-5-nitropyridine (1.0 eq) and dimethylamine (2 M in EtOH, 4.6 eq) in NMP were heated for 2 h at 100° C. The solution was then poured slowly into H2O. The filtrate that formed was filtered and dried to give 2-(dimethylamino)-5-nitropyridine.

Quelle