Reaktion #41759

ord-73c63bb40b8f4efc9c2aa5bb6326060e

Reaktionsgleichung

O=[N+]([O-])c1ccc(CCN2CCOCC2)cc1
4-[2-(4-nitrophenyl)ethyl]morpholine
→
Nc1ccc(CCN2CCOCC2)cc1
4-(2-morpholin-4-ylethyl)phenylamine

Edukte

O=[N+]([O-])c1ccc(CCN2CCOCC2)cc1
4-[2-(4-nitrophenyl)ethyl]morpholine

Reagenzien

[Pd]
Pd/C

Lösungsmittel

CO
methanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The mixture containing 4-[2-(4-nitrophenyl)ethyl]morpholine in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield 4-(2-morpholin-4-ylethyl)phenylamine. MS: MH+=206.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07728010B2uspto-grants-2010_06