Reaktion #41731

Reaktionsgleichung

hydrochloric acid

2-amino-4-methoxyphenol

O-ethylxanthic acid

potassium

→

5-methoxybenzoxazole-2-thiol

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for two hours

Vorschrift

The mixture containing 2-amino-4-methoxyphenol (1 eq) and O-ethylxanthic acid, potassium salt (1.1 eq) in pyridine was refluxed for two hours. The resultant mixture was poured in to ice/water containing hydrochloric acid to yield a 5-methoxybenzoxazole-2-thiol as a tan solid. MS: MH+=182

Quelle