Reaktion #41601

Reaktionsgleichung

hydrazine monohydrate

4-benzyloxy-3-fluoronitrobenzene

→

4-benzyloxy-3-fluoroaniline

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe reaction liquid
2. 2
   SonstigeThe catalyst was removed through filtration through Celite
3. 3
   Sonstigethe solvent was evaporated away under reduced pressure
4. 4
   Sonstigeto obtain the entitled compound as a yellow oily substance

Vorschrift

2.91 ml of hydrazine monohydrate and about 1 g of developed Raney nickel catalyst were added to a methanol (60 ml) solution of 4.94 g of 4-benzyloxy-3-fluoronitrobenzene, and the reaction liquid was stirred at room temperature for 2 hours. The catalyst was removed through filtration through Celite, and the solvent was evaporated away under reduced pressure to obtain the entitled compound as a yellow oily substance.

Quelle