Reaktion #414668

Reaktionsgleichung

6-bromo-1,2,3,4-tetrahydro-8-nitro-3-quinolinamine dihydrochloride

iodopropane

5-(amino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin

ethyl acetate

quinolin-2(1H)-one

→

5-[bis(cyclopropylmethyl)amino]-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one

Reaktionsbedingungen

Vorschrift

Following the procedure of Example 54, but substituting cyclopropylmethyl bromide for iodopropane and 5-(amino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(quinolin-2(1H)-one for 6-bromo-1,2,3,4-tetrahydro-8-nitro-3-quinolinamine dihydrochloride there were obtained 5-[bis(cyclopropylmethyl)amino]-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one, mp 152-154 from ethyl acetate:hexane and 5-(cyclopropylmethylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one. The latter compound was converted to the hydrochloride salt, mp 309° C. (dec) from methanol:ether. ##STR2##

Quelle