Reaktion #41425

ord-f6351522315f457295e38101facf3fba

Reaktionsgleichung

Ic1ccc2c(cnn2-c2ccccn2)c1
118b
Ic1ccc2c(cnn2-c2ccccn2)c1
5-Iodo-1-pyridin-2-yl-1H-indazole
NNc1ccc(Cl)nn1
3-chloro-6-hydrazinopyridazine
→
Clc1ccc(-n2ncc3cc(I)ccc32)nn1
1-(6-Chloro-pyridazin-3-yl)-5-iodo-1H-indazole

Edukte

Ic1ccc2c(cnn2-c2ccccn2)c1
118b
Ic1ccc2c(cnn2-c2ccccn2)c1
5-Iodo-1-pyridin-2-yl-1H-indazole
NNc1ccc(Cl)nn1
3-chloro-6-hydrazinopyridazine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared

Vorschrift

Prepared as described for 118b using 3-chloro-6-hydrazinopyridazine. Yield 687 mg (45%).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07728030B2uspto-grants-2010_06