Reaktion #41391

ord-9d9db886bc5e4421b3043558471c1a63

Reaktionsgleichung

CCC[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)OC
( 91d )
CCC[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)OC
(S)-tert-butyl 1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate
CC[C@H](NC(=O)OC(C)(C)C)C(=O)O
(2S)-2-[(tert-butoxycarbonyl)amino]butanoic acid
→
CC[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)OC
(S)-tert-Butyl 1-(methoxy(methyl)amino)-1-oxobutan-2-ylcarbamate

Edukte

CCC[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)OC
( 91d )
CCC[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)OC
(S)-tert-butyl 1-(methoxy(methyl)amino)-1-oxopentan-2-ylcarbamate
CC[C@H](NC(=O)OC(C)(C)C)C(=O)O
(2S)-2-[(tert-butoxycarbonyl)amino]butanoic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

was synthesised in the same way as (91d) from commercially available (2S)-2-[(tert-butoxycarbonyl)amino]butanoic acid (0.935 g, 4.60 mmol).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07728030B2uspto-grants-2010_06