Reaktion #413571

Reaktionsgleichung

3-morpholinopropylamine

2,2,6,6-tetramethyl-4-piperidone

→

N-(2,2,6,6-tetramethyl-4-piperidyl)-3-morpholinopropylamine

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigehydrogenation is carried out at 60 bar and 60° C. until the absorption of hydrogen ceases (about 15 hours)

Vorschrift

288.4 g (2 mol) of 3-morpholinopropylamine, 310.5 g (2 mol) of 2,2,6,6-tetramethyl-4-piperidone and 300 ml of methanol are introduced into a 2 litre autoclave; 15 g of 5% Pt-on-carbon are added, and hydrogenation is carried out at 60 bar and 60° C. until the absorption of hydrogen ceases (about 15 hours).

Quelle