Reaktion #412996

Reaktionsgleichung

methyl 2-propyl-6-heptenoate

sodium hydroxide

water

→

2-propyl-6-heptenoic acid

Ausbeute 75.2%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Temperaturunder reflux for 2 hours
3. 3
   SonstigeThe solvent was removed under reduced pressure
4. 4
   Extraktionextracted with ethyl acetate
5. 5
   SonstigeThe organic layer was dried
6. 6
   Einengenconcentrated

Vorschrift

A mixture of methyl 2-propyl-6-heptenoate (1.8 g), sodium hydroxide (0.65 g), water (2 ml) and ethanol (100 ml) was heated under reflux for 2 hours. The solvent was removed under reduced pressure and the resulting residue was shaken with water and hexane. The aqueous layer was acidified with concentrated hydrochloric acid and extracted with ethyl acetate. The organic layer was dried and concentrated to give oil of 2-propyl-6-heptenoic acid (1.25 g).

Quelle