Reaktion #412105

ord-626ac833fb5d4721ae958059d34fbc81

Reaktionsgleichung

O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O
fructose lactitol
COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O
aspartame
→
OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O
Lactitol

Edukte

O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O
fructose lactitol
COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O
aspartame

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.ADDITIONlast mixing step which in this case

Vorschrift

Example 2 was repeated, but instead of fructose lactitol (32.95%) was used, and aspartame (0.05%) was added in the last mixing step which in this case was performed in a Stephan mixer.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06221422B1uspto-grants-2001_04