Reaktion #411998

ord-dcbb50dafd034dc29239faca6dcaf9ea

Reaktionsgleichung

COC(=O)CC(=O)C(C)C
methyl isobutyrylacetate
O=Cc1ccc(F)cc1
4-fluorobenzaldehyde
CC(=O)[O-].[NH4+]
ammonium acetate
→
COC(=O)c1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1
Methyl 2,6diisopropyl-4-(4-fluorophenyl)-5-hydroxymethyl-3-pyridinecarboxylate

Edukte

COC(=O)CC(=O)C(C)C
methyl isobutyrylacetate
O=Cc1ccc(F)cc1
4-fluorobenzaldehyde
CC(=O)[O-].[NH4+]
ammonium acetate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared from methyl isobutyrylacetate, 4-fluorobenzaldehyde and ammonium acetate by the procedures described in Example 1, Steps A-D.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06218431B1uspto-grants-2001_04