Reaktion #409582

Reaktionsgleichung

1-[3-(4-hydroxyphenyl)propyl]imidazole

2-chloromethyl-5-phenylbenzoxazole

→

2-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-5-phenylbenzoxazole

Ausbeute 77.0%

Reaktionsbedingungen

Vorschrift

In substantially the same manner as in Working Example 72, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 2-chloromethyl-5-phenylbenzoxazole to give 2-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]-5-phenylbenzoxazole. The yield was 77%. Recrystallization from ethyl acetate-hexane gave pale yellow plates, mp 123-124° C.

Quelle