Reaktion #409329

Reaktionsgleichung

Acrylonitrile

4-cyclohexylpiperidine

→

white solid

Ausbeute 92.0%

3-(4-Cyclohexylpiperidin-1-yl)propionitrile

Ausbeute 92.0%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was removed

Vorschrift

Acrylonitrile (4.16 mL, 63.1 mmol, 2.50 equiv) was-added at 0° C. to a solution of 4-cyclohexylpiperidine (4.20 g, 25.3 mmol, 1.00 equiv) in EtOH (50 mL) and the resulting solution was stirred for 1.5 hours at room temperature. The solvent was removed to give 5.11 g (92%) of white solid, which was characterized spectroscopically and used without purification for the next reaction.

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