Reaktion #40805

ord-c8f862b8d57b4ed5a6bad16f2966582d

Reaktionsgleichung

CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1
ethyl 5-(4-ethylphenyl)-6-phenylpyridine-2-carboxylate
CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1
Compound 23
CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1
ethyl 5-(4-ethylphenyl)-6-phenylpyridine-2-carboxylate
→
CCc1ccc(-c2ccc(C(=O)OC)nc2-c2ccccc2)cc1
title compound
CCc1ccc(-c2ccc(C(=O)OC)nc2-c2ccccc2)cc1
Methyl 5-(4-Ethylphenyl)-6-phenyl-pyridine-2-carboxylate

Edukte

CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1
ethyl 5-(4-ethylphenyl)-6-phenylpyridine-2-carboxylate
CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1
Compound 23
CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1
ethyl 5-(4-ethylphenyl)-6-phenylpyridine-2-carboxylate

Reagenzien

O=S(=O)(O)O
H2SO4

Lösungsmittel

CO
MeOH

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigewere reacted

Vorschrift

Following General Procedure E, ethyl 5-(4-ethylphenyl)-6-phenylpyridine-2-carboxylate (Compound 23, 45 mg, 0.15 mmol) and conc. H2SO4 (3 drops) in MeOH (3 ml) were reacted to produce title compound as a yellow solid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07728014B2uspto-grants-2010_06