Reaktion #4073

Reaktionsgleichung

(S)-2-(6-methoxy-2-naphthyl)-propionic acid

sodium hydroxide

→

sodium (S)-2-(6-methoxy-2-naphthyl)propionate

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent is evaporated in vacuo
2. 2
   Sonstigefollowed by precipitation with ether

Vorschrift

To a solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)-propionic acid in 5 ml of methanol is added a 1 molar equivalent of sodium hydroxide, in the form of a 0.1N solution. The solvent is evaporated in vacuo and the residue is taken up in 2 ml of methanol, followed by precipitation with ether, to yield crude sodium (S)-2-(6-methoxy-2-naphthyl)propionate.

Quelle