Reaktion #40721

Reaktionsgleichung

3,6-dichloropyridazine

hydrazine hydrate

→

1-(6-chloropyridazin-3-yl)hydrazine

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for one hour
2. 2
   SonstigeThe reaction mixture was evaporated to dryness
3. 3
   Sonstigethe residue was recrystallized from benzene

Vorschrift

As shown in FIG. 5, a mixture of 40 g (0.27 mole) of 3,6-dichloropyridazine and 40 mL of 80% hydrazine hydrate in 80 mL of ethanol was refluxed for one hour. The reaction mixture was evaporated to dryness and the residue was recrystallized from benzene to give 39 g of 1-(6-chloropyridazin-3-yl)hydrazine (compound 1003) (see Takahayashi, J. Pharm. Soc. Japan 75:778-781, 1955).

Quelle