Reaktion #4069

Reaktionsgleichung

N-bromosuccinimide

methyl phenylacetate

→

title compound

Ausbeute 93.1%

Methyl Bromo-Phenylacetate

Ausbeute 93.1%

Lösungsmittel

carbon tetrachloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturto reflux
2. 2
   Temperaturrefluxed for about 12 hours
3. 3
   Filtrationfiltered
4. 4
   EinengenThe filtrate was concentrated by evaporation under vacuum

Vorschrift

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

Quelle