Reaktion #40667

Reaktionsgleichung

2d

3,3-dimethyl-1-(2-nitrophenyl)indoline

→

2e

Ausbeute 75.0%

2-(3,3-dimethylindolin-1-yl)benzenamine

Ausbeute 75.0%

Lösungsmittel

MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst was filtered through a cake of Celite®
2. 2
   Sonstigethe filtrate was evaporated under reduced pressure

Vorschrift

To a solution of 2d (123 mg, 0.458 mmol) in MeOH was added 10% Pd/C (20 mg). The reaction mixture was stirred at rt under H2 for 2 h. The catalyst was filtered through a cake of Celite® and the filtrate was evaporated under reduced pressure to afford 2e (80 mg, 75%) as a yellowish powder. MS (ES) m/z 239 [M+H]+.

Quelle