Reaktion #40633
ord-c4849fba64a44787b6809841dc512196
Reaktionsgleichung
3-morpholin-4-yl-propylamine
8-cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
→
8-Cyclohexyl-2-(3-morpholin-4-yl-propylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
Using the procedure outlined in Example 28 Step F, the title compound was prepared from 3-morpholin-4-yl-propylamine and 8-cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester (from Example 35 Step E, 20 mg, 0.045 mmol). 8-Cyclohexyl-2-(3-morpholin-4-yl-propylamino)-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester was obtained as a white solid (18 mg, 85%). Mass Spectrum (LCMS, ESI pos.) Calcd. For C23H33N5O4: 444.25 (M+H). Found: 4444.3.