Reaktion #40301

ord-4a9b7976539f4e5b878d784e3b817458

Reaktionsgleichung

CC1(C)C=CC(=O)CC1
4,4-dimethyl-cyclohex-2-enone
[H][H]
hydrogen
→
CC1(C)CCC(=O)CC1
4,4-dimethyl-cyclohexanone
Ausbeute 94.0%

Edukte

CC1(C)C=CC(=O)CC1
4,4-dimethyl-cyclohex-2-enone
[H][H]
hydrogen

Reagenzien

[Pd]
Pd/C

Lösungsmittel

CCOC(C)=O
ethyl acetate

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    FiltrationFiltration over celite
  2. 2
    Einengenconcentration
  3. 3
    Sonstigeby evaporation

Vorschrift

A solution of 4,4-dimethyl-cyclohex-2-enone (3 mmol) in ethyl acetate is hydrogenated overnight at room temperature using Pd/C (0.05 mmol) with hydrogen under normal pressure. Filtration over celite and then concentration by evaporation produces 4,4-dimethyl-cyclohexanone (355 mg) in a yield of 94% (J. Org. Chem. 2001, 66 (3), 733-738).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07727979B2uspto-grants-2010_06