Reaktion #4030

Reaktionsgleichung

p-(5-octylpyridyl)benzoic acid

thionyl chloride

→

p-(5-octylpyridyl)benzoylchloride hydrochloride

Ausbeute 96.7%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturreflux
2. 2
   Temperaturwas maintained for 5 hours
3. 3
   SonstigeThe surplus thionyl chloride was removed by distillation
4. 4
   Sonstigethe product was recrystallized from hexane

Vorschrift

30 g (0.102 mol) of the resulting p-(5-octylpyridyl)benzoic acid was added to 24.3 g (0.204 mol) of thionyl chloride and reflux was maintained for 5 hours. The surplus thionyl chloride was removed by distillation and the product was recrystallized from hexane to obtain 34.5 g (0.0986 mol) of p-(5-octylpyridyl)benzoylchloride hydrochloride.

Quelle