Reaktion #40286

Reaktionsgleichung

Acetic anhydride

β-alanine

acetonitrile

acetic anhydride

→

N-Acetyl-β-alanine

Lösungsmittel

NaHCO3

Reaktionsbedingungen

Vorschrift

To a solution of β-alanine (2.25 g, 25 mmol) in aq. NaHCO3 (15 mL) was added acetonitrile (15 mL) and acetic anhydride (2.55 g, 25 mmol). The reaction mixture was stirred at room temperature for 3 h. Acetic anhydride (2.55 g, 25 mmol) was added and after 2 h and pH was adjusted to 4-5 by addition of NaH2PO4.

Quelle