Reaktion #40284

Reaktionsgleichung

N-Boc-β-alanine

propargyl alcohol

Dicyclohexyl-carbodiimide

→

N-Boc-β-alanine Propargyl Ester

Lösungsmittel

EtOAc

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe reaction mixture was filtered
2. 2
   Sonstigeevaporated to dryness under vacuum
3. 3
   SonstigeCrude product yield

Vorschrift

N-Boc-β-alanine (1.91 g, 10.1 mmol) and propargyl alcohol (0.675 g, 12 mmol) were dissolved in EtOAc (25 mL). Dicyclohexyl-carbodiimide (DCC, 2.06 g, 10 mmol) was added to the solution and after 16 h of stirring at room temperature, the reaction mixture was filtered and evaporated to dryness under vacuum. Crude product yield

Quelle