Reaktion #3856

ord-b296aa432e43463e8f3c1a0d26a6db83

Reaktionsgleichung

O=C([O-])[O-].[Na+].[Na+]
sodium carbonate
Clc1nc(Cl)nc(Cl)n1
cyanuric chloride
CCC(C)NCCN1CC(C)(C)NC(C)(C)C1=O
1-[2-(2-butylamino)ethyl]-3,3,5,5-tetramethyl-2-piperazinone
→
CCC(C)N(CCN1CC(C)(C)NC(C)(C)C1=O)c1nc(Cl)nc(Cl)n1
2,4-dichloro-6-[1-methylpropyl[2-(3,3,5,5-tetramethyl-2-oxo-1-piperazinyl)ethyl]amino]-1,3,5-triazine

Edukte

O=C([O-])[O-].[Na+].[Na+]
sodium carbonate
Clc1nc(Cl)nc(Cl)n1
cyanuric chloride
CCC(C)NCCN1CC(C)(C)NC(C)(C)C1=O
1-[2-(2-butylamino)ethyl]-3,3,5,5-tetramethyl-2-piperazinone

Reagenzien

Keine

Lösungsmittel

CC(C)=O
acetone
O
water
O
water
CC(C)=O
acetone
O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeIn a 1 liter three-necked flask were placed
  2. 2
    SonstigeA white slurry formed which
  3. 3
    workup.ADDITIONwhile adding to it dropwise
  4. 4
    workup.ADDITIONThe addition

Vorschrift

In a 1 liter three-necked flask were placed 300 ml of water which was cooled to 1° C. 46.1 g (0.25 mole) of cyanuric chloride was dissolved in 240 ml acetone and added to the water in the flask. A white slurry formed which was stirred while adding to it dropwise, 63.9 g (0.25 mole) of 1-[2-(2-butylamino)ethyl]-3,3,5,5-tetramethyl-2-piperazinone in 60 ml acetone and 13.3 g of sodium carbonate in 60 ml water. The addition took about 30 min.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04722806uspto-grants-1988_02