Reaktion #3842

Reaktionsgleichung

2-mercaptobenzophenone

diethyl azodicarboxylate

→

title compound

Ausbeute 50.7%

[2-(2-Benzoyl-phenyldisulfanyl)-phenyl]-phenyl-methanone

Ausbeute 50.7%

Lösungsmittel

benzene

diethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturrefluxed for 16 hours
2. 2
   TemperaturThe solution was cooled
3. 3
   Einengenconcentrated in vacuo
4. 4
   Sonstigeleaving a yellow liquid
5. 5
   SonstigeThe crude product was purified

Vorschrift

To a solution of 2-mercaptobenzophenone (2.3 g, 7.4 mmol) in diethyl ether (10 mL) was added dropwise diethyl azodicarboxylate (0.65 g, 3.7 mmol). The solution was stirred for 5 minutes at room temperature, then diluted with benzene (40 mL) and refluxed for 16 hours. The solution was cooled and concentrated in vacuo leaving a yellow liquid. The crude product was purified using silica gel chromatography (75% hexane/25% ethyl acetate) to give the title compound as a yellow foam (0.8 g, 50%);

Quelle