Reaktion #3742

Reaktionsgleichung

2, 3-dicyano-pyrazine

isobutylene

sulfuric acid

→

N-tert-butyl-2-pyrazinecarboxamide

3-cyano-N-tert-butyl-2-pyrazinecarboxamide

Lösungsmittel

tert-butyl alcohol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigecan be obtained

Vorschrift

A compound having the formula (4) can be obtained as follows. The corresponding 2, 3-dicyano-pyrazine is reacted with tert-butyl alcohol or isobutylene in the presence of sulfuric acid to obtain the corresponding N-tert-butyl-2-pyrazinecarboxamide and/or 3-cyano-N-tert-butyl-2-pyrazinecarboxamide. Then, thus obtained corresponding N-tert-butyl-2-pyrazinecarboxamide and/or 3-cyano-N-tert-butyl-2-pyrazinecarboxamide are hydrolyzed under an alkaline condition.

Quelle