Reaktion #3738

ord-712a4c23c26a4619a1659f080875532d

Reaktionsgleichung

O=c1c2[nH]c([N+](=O)[O-])nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1
1,3-di-cyclohexylmethyl-8-nitro xanthine
Br
hydrobromic acid
O=c1c2[nH]c(Br)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1
title product
O=c1c2[nH]c(Br)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1
1,3-Di-cyclohexylmethyl-8-bromo Xanthine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 1,3-di-cyclohexylmethyl-8-nitro xanthine (1 g, 0.0026 mol) and concentrated hydrobromic acid (40 ml, 48%) over 32 hours using an analogous procedure to that described in Example 15. The title product was obtained as a crystalline solid, m.pt. 247° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05734051uspto-grants-1998_03