Reaktion #3737

ord-bc2d669ae91a4d3ca99ba757588a1739

Reaktionsgleichung

O=c1c2[nH]c(Br)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1
1,3-di-cyclohexylmethyl-8-bromo xanthine
C1CCNCC1
piperidine
O=c1c2[nH]c(N3CCCCC3)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1
title product
O=c1c2[nH]c(N3CCCCC3)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1
1,3-Di-cyclohexylmethyl-8-piperidinyl Xanthine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 1,3-di-cyclohexylmethyl-8-bromo xanthine (0.7 g, 0.0017 mol) and piperidine (0.28 g, 0,003 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. 266° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05734051uspto-grants-1998_03